A shape-based approach to the segmentation of medical imagery using level sets

We propose a shape-based approach to curve evolution for the segmentation of medical images containing known object types. In particular, motivated by the work of Leventon, Grimson, and Faugeras, we derive a parametric model for an implicit representation of the segmenting curve by applying principal component analysis to a collection of signed distance representations of the training data. The parameters of this representation are then manipulated to minimize an objective function for segmentation. The resulting algorithm is able to handle multidimensional data, can deal with topological changes of the curve, is robust to noise and initial contour placements, and is computationally efficient. At the same…

• NS
  National Science Foundation
• JH
  Johns Hopkins University
• NI
  National Institutes of Health
• OO
  Office of Naval Research

  Award: N00014
• AF
  Air Force Office of Scientific Research

  Award: F49620