Tools of the trade: psychophysiological interactions and functional connectivity
Wellcome Centre for Integrative Neuroimaging · National Hospital for Neurology and Neurosurgery · +5 more institutions
Abstract
Psychophysiological interactions (PPIs) analysis is a method for investigating task-specific changes in the relationship between activity in different brain areas, using functional magnetic resonance imaging (fMRI) data. Specifically, PPI analyses identify voxels in which activity is more related to activity in a seed region of interest (seed ROI) in a given psychological context, such as during attention or in the presence of emotive stimuli. In this tutorial, we aim to give a simple conceptual explanation of how PPI analysis works, in order to assist readers in planning and interpreting their own PPI experiments.
Citation impact
- FWCI
- 18.82
- Percentile
- 100%
- References
- 41
Authors
5- JXJill X. O’ReillyCorresponding
Wellcome Centre for Integrative Neuroimaging, National Hospital for Neurology and Neurosurgery, Wellcome Centre for Human Neuroimaging, John Radcliffe Hospital, University College London, University of Oxford, Warneford Hospital
- MWMark W. Woolrich
Warneford Hospital, University of Oxford, Wellcome Centre for Integrative Neuroimaging, University College London, John Radcliffe Hospital, National Hospital for Neurology and Neurosurgery, Wellcome Centre for Human Neuroimaging
- TETimothy E.J. Behrens
National Hospital for Neurology and Neurosurgery, Warneford Hospital, University College London, John Radcliffe Hospital, Wellcome Centre for Integrative Neuroimaging, University of Oxford, Wellcome Centre for Human Neuroimaging
- SMStephen M. Smith
Wellcome Centre for Human Neuroimaging, Wellcome Centre for Integrative Neuroimaging, National Hospital for Neurology and Neurosurgery, Warneford Hospital, John Radcliffe Hospital, University of Oxford, University College London
- HJHeidi Johansen‐Berg
National Hospital for Neurology and Neurosurgery, Wellcome Centre for Human Neuroimaging, John Radcliffe Hospital, Wellcome Centre for Integrative Neuroimaging, University College London, University of Oxford, Warneford Hospital
Topics & keywords
- Functional magnetic resonance imaging
- Psychology
- Emotive
- Context (archaeology)
- Cognitive psychology
- Functional connectivity
- Task (project management)
- Voxel