Forna (force-directed RNA): Simple and effective online RNA secondary structure diagrams
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Abstract
MOTIVATION: The secondary structure of RNA is integral to the variety of functions it carries out in the cell and its depiction allows researchers to develop hypotheses about which nucleotides and base pairs are functionally relevant. Current approaches to visualizing secondary structure provide an adequate platform for the conversion of static text-based representations to 2D images, but are limited in their offer of interactivity as well as their ability to display larger structures, multiple structures and pseudoknotted structures. RESULTS: In this article, we present forna, a web-based tool for displaying RNA secondary structure which allows users to easily convert sequences and secondary structures to…
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Authors
3Topics & keywords
Topics
Keywords
- Computer science
- Visualization
- Nucleic acid secondary structure
- Software
- Source code
- Simple (philosophy)
- Interactivity
- Protein secondary structure
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