Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications
Iowa State University · Ames National Laboratory
Abstract
Abstract Recent advancements in morphology control and surface functionalization of mesoporous silica nanoparticles (MSNs) have enhanced the biocompatibility of these materials with high surface areas and pore volumes. Several recent reports have demonstrated that the MSNs can be efficiently internalized by animal and plant cells. The functionalization of MSNs with organic moieties or other nanostructures brings controlled release and molecular recognition capabilities to these mesoporous materials for drug/gene delivery and sensing applications, respectively. Herein, we review recent research progress on the design of functional MSN materials with various mechanisms of controlled release, along with the…
Citation impact
- FWCI
- 46.22
- Percentile
- 100%
- References
- 64
Authors
4Topics & keywords
- Materials science
- Nanotechnology
- Mesoporous silica
- Surface modification
- Drug delivery
- Biocompatibility
- Nanoparticle
- Mesoporous material