articleAnesthesiologyJan 1, 2008BRONZE OA

Predictors of Cognitive Dysfunction after Major Noncardiac Surgery

Veterans Health Administration · University of Florida Health · +10 more institutions

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Abstract

Background

The authors designed a prospective longitudinal study to investigate the hypothesis that advancing age is a risk factor for postoperative cognitive dysfunction (POCD) after major noncardiac surgery and the impact of POCD on mortality in the first year after surgery.

Methods

One thousand sixty-four patients aged 18 yr or older completed neuropsychological tests before surgery, at hospital discharge, and 3 months after surgery. Patients were categorized as young (18-39 yr), middle-aged (40-59 yr), or elderly (60 yr or older). At 1 yr after surgery, patients were contacted to determine their survival status.

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