articleNew England Journal of MedicineJun 6, 2007Closed access

Explaining the Decrease in U.S. Deaths from Coronary Disease, 1980–2000

National Center for Chronic Disease Prevention and Health Promotion · Centers for Disease Control and Prevention · +3 more institutions

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Abstract

Background

Mortality from coronary heart disease in the United States has decreased substantially in recent decades. We conducted a study to determine how much of this decrease could be explained by the use of medical and surgical treatments as opposed to changes in cardiovascular risk factors.

Methods

We applied a previously validated statistical model, IMPACT, to data on the use and effectiveness of specific cardiac treatments and on changes in risk factors between 1980 and 2000 among U.S. adults 25 to 84 years old. The difference between the observed and expected number of deaths from coronary heart disease in 2000 was distributed among the treatments and risk factors included in the analyses.

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