Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta‐analysis

Metabolic syndrome (MetS) and its components are highly predictive of cardiovascular diseases. The primary aim of this systematic review and meta-analysis was to assess the prevalence of MetS and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder, comparing subjects with different disorders and taking into account demographic variables and psychotropic medication use. The secondary aim was to compare the MetS prevalence in persons with any of the selected disorders versus matched general population controls. The pooled MetS prevalence in people with severe mental illness was 32.6% (95% CI: 30.8%-34.4%; N = 198; n = 52,678). Relative risk…

• YU
  Yale University
• UO
  University of Pittsburgh
• UO
  University of Rochester
• PI
  Postgraduate Institute of Medical Education and Research, Chandigarh
• NU
  Newcastle University
• RG
  Rijksuniversiteit Groningen
• UU
  Universiteit Utrecht
• VU
  Vrije Universiteit Amsterdam
• UO
  University of Toronto
• KY
  Kuopion Yliopistollinen Sairaala
• TM
  Taipei Medical University
• UO
  University of California, San Diego
• MC
  Medical Center, University of Rochester