reviewModern RheumatologyAug 31, 2011HYBRID OA

A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details

HUHisanori UmeharaKOKazuichi OkazakiYMYasufumi MasakiMKMitsuhiro KawanoMYMotohisa Yamamoto

Kanazawa Medical University · Kansai Medical University · +14 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

IgG4-related disease (IgG4RD) is a novel clinical disease entity characterized by elevated serum IgG4 concentration and tumefaction or tissue infiltration by IgG4-positive plasma cells. IgG4RD may be present in a certain proportion of patients with a wide variety of diseases, including Mikulicz's disease, autoimmune pancreatitis, hypophysitis, Riedel thyroiditis, interstitial pneumonitis, interstitial nephritis, prostatitis, lymphadenopathy, retroperitoneal fibrosis, inflammatory aortic aneurysm, and inflammatory pseudotumor. Although IgG4RD forms a distinct, clinically independent disease category and is attracting strong attention as a new clinical entity, many questions and problems still remain to be…

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719
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40.49
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100%
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22

Topics & keywords

Topics
Keywords
  • Medicine
  • IgG4-related disease
  • Autoimmune pancreatitis
  • Retroperitoneal fibrosis
  • Pathology
  • Disease
  • Granulomatosis with polyangiitis
  • Pathogenesis
UN Sustainable Development Goals
  • Good health and well-being
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