reviewDalton TransactionsNov 21, 2008Closed access

Transition metal catalysed reactions of alcohols using borrowing hydrogen methodology

TNT.D. NixonMKMichael K. WhittleseyJMJonathan M. J. Williams

University of Bath

PubMed
Indexed incrossrefpubmed

Abstract

The reactivity of alcohols can be enhanced by the temporary removal of hydrogen using a transition metal catalyst to generate an intermediate aldehyde or ketone. The so-formed carbonyl compound has a greater reactivity towards nucleophilic addition accommodating the in situ formation of imines or alkenes. The return of hydrogen from the catalyst leads to the formation of new C-N and C-C bonds, often with water as the only reaction by-product.

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665
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100%
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Authors

3

Topics & keywords

Topics
Keywords
  • Reactivity (psychology)
  • Catalysis
  • Aldehyde
  • Chemistry
  • Ketone
  • Nucleophile
  • Transition metal
  • Hydrogen
UN Sustainable Development Goals
  • Clean water and sanitation
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