Age of Transfused Blood in Critically Ill Adults
Université du Québec à Montréal · Centre Hospitalier Universitaire Sainte-Justine · +17 more institutions
Abstract
Fresh red cells may improve outcomes in critically ill patients by enhancing oxygen delivery while minimizing the risks of toxic effects from cellular changes and the accumulation of bioactive materials in blood components during prolonged storage.
In this multicenter, randomized, blinded trial, we assigned critically ill adults to receive either red cells that had been stored for less than 8 days or standard-issue red cells (the oldest compatible units available in the blood bank). The primary outcome measure was 90-day mortality.
Citation impact
- FWCI
- 50.12
- Percentile
- 100%
- References
- 38
Authors
21- JLJacques LacroixCorresponding
Université du Québec à Montréal, Centre Hospitalier Universitaire Sainte-Justine, Centre Hospitalier de l’Université de Montréal, Université de Montréal
- PCPaul C. Hébert
Centre Hospitalier de l’Université de Montréal
- DFDean Fergusson
University of Ottawa, Ottawa Hospital
- ATAlan Tinmouth
University of Ottawa, Ottawa Hospital
- DJDeborah J. Cook
McMaster University
Topics & keywords
- Medicine
- Hazard ratio
- Confidence interval
- Red blood cell
- Surgery
- Anesthesia
- Internal medicine
- Good health and well-being