Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
VA Greater Los Angeles Healthcare System · University of California, Los Angeles
Abstract
Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant, commonly known as turmeric. Curcumin has been used extensively in Ayurvedic medicine for centuries, as it is nontoxic and has a variety of therapeutic properties including anti-oxidant, analgesic, anti-inflammatory and antiseptic activity. More recently curcumin has been found to possess anti-cancer activities via its effect on a variety of biological pathways involved in mutagenesis, oncogene expression, cell cycle regulation, apoptosis, tumorigenesis and metastasis. Curcumin has shown anti-proliferative effect in multiple cancers, and is an inhibitor of the transcription factor NF-κB and downstream gene products (including…
Citation impact
- FWCI
- 17.45
- Percentile
- 100%
- References
- 223
Authors
4- RWReason WilkenCorresponding
VA Greater Los Angeles Healthcare System
- MSMysore S. Veena
University of California, Los Angeles, VA Greater Los Angeles Healthcare System
- MBMarilene B. Wang
University of California, Los Angeles, VA Greater Los Angeles Healthcare System
- ESEri S. Srivatsan
University of California, Los Angeles, VA Greater Los Angeles Healthcare System
Topics & keywords
- Curcumin
- Head and neck squamous-cell carcinoma
- Cancer research
- Cancer
- Oncogene
- Biology
- Carcinogenesis
- Metastasis
- Good health and well-being