articleNew England Journal of MedicineAug 27, 2014BRONZE OA

Cardiovascular Risk and Events in 17 Low-, Middle-, and High-Income Countries

Chinese Academy of Medical Sciences & Peking Union Medical College · Population Health Research Institute · +31 more institutions

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Abstract

Background

More than 80% of deaths from cardiovascular disease are estimated to occur in low-income and middle-income countries, but the reasons are unknown.

Methods

We enrolled 156,424 persons from 628 urban and rural communities in 17 countries (3 high-income, 10 middle-income, and 4 low-income countries) and assessed their cardiovascular risk using the INTERHEART Risk Score, a validated score for quantifying risk-factor burden without the use of laboratory testing (with higher scores indicating greater risk-factor burden). Participants were followed for incident cardiovascular disease and death for a mean of 4.1 years.

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