articleMolecular Biology and EvolutionOct 16, 2013BRONZE OA

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

KTKoichiro TamuraGSGlen StecherDSDaniel S. PetersonAFAlan FilipskiSKSudhir Kumar

Tokyo Metropolitan University · Arizona State University · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

The Molecular Evolutionary Genetics Analysis (MEGA) software has matured to contain a large collection of methods and tools of computational molecular evolution. Here, we describe new additions that make MEGA a more comprehensive tool for building timetrees of species, pathogens, and gene families using rapid relaxed-clock methods. Methods for estimating divergence times and confidence intervals are implemented to use probability densities for calibration constraints for node-dating and sequence sampling dates for tip-dating analyses. They are supported by new options for tagging sequences with spatiotemporal sampling information, an expanded interactive Node Calibrations Editor, and an extended Tree Explorer…

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Topics & keywords

Topics
Keywords
  • Biology
  • Phylogenetic tree
  • Mega-
  • Phylogenetics
  • Divergence (linguistics)
  • Inference
  • Wizard
  • Graphical user interface
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