The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report

Cohn, Susan L.; Pearson, Andrew D.J.; London, Wendy B.; Monclair, Tom; Ambros, Peter F.; Brodeur, Garrett M.; Faldum, Andreas; Hero, Barbara; Iehara, Tomoko; Machin, David; Mosseri, Véronique; Simon, Thorsten; Garaventa, Alberto; Castel, Victoria; Matthay, Katherine K.

doi:10.1200/jco.2008.16.6785

articleJournal of Clinical OncologyDec 2, 2008Closed access

The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report

SLSusan L. Cohn ADAndrew D.J. Pearson WBWendy B. London TMTom Monclair PFPeter F. Ambros

Children's Oncology Group

PubMed

Indexed incrossrefpubmed

Abstract

PURPOSE: Because current approaches to risk classification and treatment stratification for children with neuroblastoma (NB) vary greatly throughout the world, it is difficult to directly compare risk-based clinical trials. The International Neuroblastoma Risk Group (INRG) classification system was developed to establish a consensus approach for pretreatment risk stratification. PATIENTS AND METHODS: The statistical and clinical significance of 13 potential prognostic factors were analyzed in a cohort of 8,800 children diagnosed with NB between 1990 and 2002 from North America and Australia (Children's Oncology Group), Europe (International Society of Pediatric Oncology Europe Neuroblastoma Group and German…

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Topics

Keywords

Medicine
Neuroblastoma
Internal medicine
Oncology
Cohort
Risk stratification

UN Sustainable Development Goals

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