Transmission of Equine Influenza Virus to Dogs
Centers for Disease Control and Prevention · Cornell University · +4 more institutions
Abstract
Molecular and antigenic analyses of three influenza viruses isolated from outbreaks of severe respiratory disease in racing greyhounds revealed that they are closely related to H3N8 equine influenza virus. Phylogenetic analysis indicated that the canine influenza virus genomes form a monophyletic group, consistent with a single interspecies virus transfer. Molecular changes in the hemagglutinin suggested adaptive evolution in the new host. The etiologic role of this virus in respiratory disease was supported by the temporal association of rising antibody titers with disease and by experimental inoculation studies. The geographic expansion of the infection and its persistence for several years indicate…
Citation impact
- FWCI
- 15.27
- Percentile
- 100%
- References
- 26
Authors
19- PCP.C. CrawfordCorresponding
Centers for Disease Control and Prevention, Cornell University, University of Florida, New York State College of Veterinary Medicine, Auburn University, Texas A&M University
- EJEdward J. Dubovi
Centers for Disease Control and Prevention, Cornell University, University of Florida, New York State College of Veterinary Medicine, Auburn University, Texas A&M University
- WLWilliam L. Castleman
Centers for Disease Control and Prevention, Cornell University, University of Florida, New York State College of Veterinary Medicine, Auburn University, Texas A&M University
- ISIain Stephenson
Centers for Disease Control and Prevention, Cornell University, University of Florida, New York State College of Veterinary Medicine, Auburn University, Texas A&M University
- EPE. P. J. Gibbs
Centers for Disease Control and Prevention, Cornell University, University of Florida, New York State College of Veterinary Medicine, Auburn University, Texas A&M University
Topics & keywords
- Virology
- Virus
- Biology
- Equine influenza
- Enzootic
- Outbreak
- Population
- Transmission (telecommunications)
- Good health and well-being