reviewJNCI MonographsOct 1, 2010BRONZE OA

Overview of the Randomized Trials of Radiotherapy in Ductal Carcinoma In Situ of the Breast

EBEarly Breast Cancer Trialists' Collaborative Group (EBCTCG)
PubMed
Indexed incrossrefpubmed

Abstract

Individual patient data were available for all four of the randomized trials that began before 1995, and that compared adjuvant radiotherapy vs no radiotherapy following breast-conserving surgery for ductal carcinoma in situ (DCIS). A total of 3729 women were eligible for analysis. Radiotherapy reduced the absolute 10-year risk of any ipsilateral breast event (ie, either recurrent DCIS or invasive cancer) by 15.2% (SE 1.6%, 12.9% vs 28.1% 2 P

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668
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Authors

1
  • EB
    Early Breast Cancer Trialists' Collaborative Group (EBCTCG)Corresponding

Topics & keywords

Topics
Keywords
  • Medicine
  • Breast cancer
  • Ductal carcinoma
  • Tamoxifen
  • Radiation therapy
  • Breast-conserving surgery
  • Absolute risk reduction
  • Randomized controlled trial
UN Sustainable Development Goals
  • Good health and well-being
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