Influence of Child Abuse on Adult Depression

Bradley, Rebekah; Binder, Elisabeth B.; Epstein, Michael P.; Tang, Yi‐lang; Nair, Hemu P; Liu, Wei; Gillespie, Charles F.; Berg, Tiina; Evces, Mark; Newport, D. Jeffrey; Stowe, Zachary N.; Heim, Christine M.; Nemeroff, Charles B.; Schwartz, Ann C.; Cubells, Joseph F.; Ressler, Kerry J.

doi:10.1001/archgenpsychiatry.2007.26

articleArchives of General PsychiatryFeb 1, 2008GREEN OA

Influence of Child Abuse on Adult Depression

RBRebekah Bradley EBElisabeth B. Binder MPMichael P. Epstein YTYi‐lang Tang HPHemu P Nair

Atlanta Medical Center · Atlanta VA Medical Center

PubMed

Indexed incrossrefpubmed

Abstract

Objective

To examine whether the effects of child abuse on adult depressive symptoms are moderated by genetic polymorphisms within the corticotropin-releasing hormone type 1 receptor (CRHR1) gene.

Design

Association study examining gene x environment interactions between genetic polymorphisms at the CRHR1 locus and measures of child abuse on adult depressive symptoms.

Citation impact

641

total citations

FWCI: 20.61
Percentile: 100%
References: 50

Citations per year

Authors

16

Topics & keywords

Topics

Keywords

Population
Haplotype
Single-nucleotide polymorphism
Psychiatry
Psychology
Clinical psychology
Medicine
Genetics

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