CDD: NCBI's conserved domain database
National Institutes of Health · National Center for Biotechnology Information
Abstract
NCBI's CDD, the Conserved Domain Database, enters its 15(th) year as a public resource for the annotation of proteins with the location of conserved domain footprints. Going forward, we strive to improve the coverage and consistency of domain annotation provided by CDD. We maintain a live search system as well as an archive of pre-computed domain annotation for sequences tracked in NCBI's Entrez protein database, which can be retrieved for single sequences or in bulk. We also maintain import procedures so that CDD contains domain models and domain definitions provided by several collections available in the public domain, as well as those produced by an in-house curation effort. The curation effort aims at…
Citation impact
- FWCI
- 159.48
- Percentile
- 100%
- References
- 14
Authors
20- AMAron Marchler‐BauerCorresponding
National Institutes of Health, National Center for Biotechnology Information
- MKMyra K. Derbyshire
National Center for Biotechnology Information, National Institutes of Health
- NRNoreen R. Gonzales
National Institutes of Health, National Center for Biotechnology Information
- SLShennan Lu
National Institutes of Health, National Center for Biotechnology Information
- FCFarideh Chitsaz
National Institutes of Health, National Center for Biotechnology Information
Topics & keywords
- Annotation
- Domain (mathematical analysis)
- Biology
- Public domain
- Protein domain
- Consistency (knowledge bases)
- Computational biology
- Database