articleCell Communication and SignalingMay 14, 2011GOLD OA

Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

RHRalf HassCKCornelia KasperSBStefanie BöhmRJRoland Jacobs

Medizinische Hochschule Hannover · Leibniz University Hannover

PubMed
Indexed incrossrefdatacitedoajpubmed

Abstract

The mesenchymal stroma harbors an important population of cells that possess stem cell-like characteristics including self renewal and differentiation capacities and can be derived from a variety of different sources. These multipotent mesenchymal stem cells (MSC) can be found in nearly all tissues and are mostly located in perivascular niches. MSC have migratory abilities and can secrete protective factors and act as a primary matrix for tissue regeneration during inflammation, tissue injuries and certain cancers.These functions underlie the important physiological roles of MSC and underscore a significant potential for the clinical use of distinct populations from the various tissues. MSC derived from…

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Topics & keywords

Topics
Keywords
  • Mesenchymal stem cell
  • Biology
  • Cell biology
  • Stem cell
  • Population
  • Immunology
  • Bone marrow
  • Adipose tissue
UN Sustainable Development Goals
  • Good health and well-being
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