The Genome of the Sea Urchin Strongylocentrotus purpuratus
California Institute of Technology · National Institutes of Health · +31 more institutions
Abstract
We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The genome encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside the deuterostomes. This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes.
Citation impact
- FWCI
- 160.73
- Percentile
- 100%
- References
- 45
Authors
228- ESErica Sodergren
California Institute of Technology, National Institutes of Health, Baylor College of Medicine, Stazione Zoologica Anton Dohrn, National Institute of Dental and Craniofacial Research
- GMGeorge M. WeinstockCorresponding
California Institute of Technology, National Institutes of Health, Baylor College of Medicine, Stazione Zoologica Anton Dohrn, National Institute of Dental and Craniofacial Research
- EHEric H. Davidson
California Institute of Technology, National Institutes of Health, Baylor College of Medicine, Stazione Zoologica Anton Dohrn, National Institute of Dental and Craniofacial Research
- RAR. Andrew Cameron
California Institute of Technology, National Institutes of Health, Baylor College of Medicine, Stazione Zoologica Anton Dohrn, National Institute of Dental and Craniofacial Research
- RARichard A. Gibbs
California Institute of Technology, National Institutes of Health, Baylor College of Medicine, Stazione Zoologica Anton Dohrn, National Institute of Dental and Craniofacial Research
Topics & keywords
- Strongylocentrotus purpuratus
- Biology
- Genome
- Sea urchin
- Evolutionary biology
- Echinoderm
- Vertebrate
- Genetics
- Life below water