Newborn Screening for Severe Combined Immunodeficiency in 11 Screening Programs in the United States
University of California, San Francisco · UCSF Benioff Children's Hospital · +48 more institutions
Abstract
Newborn screening for severe combined immunodeficiency (SCID) using assays to detect T-cell receptor excision circles (TRECs) began in Wisconsin in 2008, and SCID was added to the national recommended uniform panel for newborn screened disorders in 2010. Currently 23 states, the District of Columbia, and the Navajo Nation conduct population-wide newborn screening for SCID. The incidence of SCID is estimated at 1 in 100,000 births.
To present data from a spectrum of SCID newborn screening programs, establish population-based incidence for SCID and other conditions with T-cell lymphopenia, and document early institution of effective treatments.
Citation impact
- FWCI
- 25.03
- Percentile
- 100%
- References
- 51
Authors
79- AKAntonia Kwan
University of California, San Francisco, UCSF Benioff Children's Hospital
- RSRoshini S. Abraham
Mayo Clinic
- RJRobert J. Currier
California Department of Public Health
- ABAmy Brower
American College of Medical Genetics, Research Network (United States)
- KAKaren Andruszewski
Michigan Department of Health and Human Services
Topics & keywords
- Medicine
- Newborn screening
- Severe combined immunodeficiency
- Incidence (geometry)
- Pediatrics
- Population
- Environmental health
- Good health and well-being