articleAngewandte Chemie International EditionMar 12, 2013Closed access

NIR‐Triggered Anticancer Drug Delivery by Upconverting Nanoparticles with Integrated Azobenzene‐Modified Mesoporous Silica

Chinese Academy of Sciences · Shanghai Institute of Ceramics

PubMed
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Abstract

Photomediated drug release: Silica-coated upconverting nanoparticles with mesopores modified by azobenzene molecules were synthesized. The azobenzene molecules make possible the release of the anticancer drug doxorubicin from the pore network of the mesoporous silica outer layer by irradiation with near-infrared (NIR) laser light. The release is regulated by the trans–cis photoisomerization of the azobenzene molecules (see picture). As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting…

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