Brain?Gut?Microbe Communication in Health and Disease

Bidirectional signalling between the gastrointestinal tract and the brain is regulated at neural, hormonal, and immunological levels. This construct is known as the brain-gut axis and is vital for maintaining homeostasis. Bacterial colonization of the intestine plays a major role in the post-natal development and maturation of the immune and endocrine systems. These processes are key factors underpinning central nervous system (CNS) signaling. Recent research advances have seen a tremendous improvement in our understanding of the scale, diversity, and importance of the gut microbiome. This has been reflected in the form of a revised nomenclature to the more inclusive brain-gut-enteric microbiota axis and a…

• G
  GlaxoSmithKline
• AN
  American Neurogastroenterology and Motility Society
• SF
  Science Foundation Ireland

  Awards: 02/CE/B124, 07/CE/B1368