New Principles for Glycoside‐Bond Formation

Abstract Meeting the demand for sugars : The importance of oligosaccharides and glycoconjugates in biological systems has stimulated a need to access significant amounts of these compounds. Much effort has been devoted to the stereoselective generation of the key glycosidic bond, both between carbohydrate residues (see scheme) and to the aglycone. Various methodologies are now available for the efficient synthesis of structurally defined complex oligosaccharides and glycoconjugates. magnified image Increased understanding of the important roles that oligosaccharides and glycoconjugates play in biological processes has led to a demand for significant amounts of these materials for biological, medicinal, and…