Concentrations of Urinary Phthalate Metabolites Are Associated with Increased Waist Circumference and Insulin Resistance in Adult U.S. Males

Stahlhut, Richard W.; Wijngaarden, Edwin van; Dye, Timothy; Cook, Stephen; Swan, Shanna H.

doi:10.1289/ehp.9882

articleEnvironmental Health PerspectivesMar 13, 2007DIAMOND OA

Concentrations of Urinary Phthalate Metabolites Are Associated with Increased Waist Circumference and Insulin Resistance in Adult U.S. Males

RWRichard W. Stahlhut EVEdwin van Wijngaarden TDTimothy Dye SCStephen Cook SHShanna H. Swan

University of Rochester

PubMed

Indexed incrossrefdoajpubmed

Abstract

Background

Phthalates impair rodent testicular function and have been associated with anti-androgenic effects in humans, including decreased testosterone levels. Low testosterone in adult human males has been associated with increased prevalence of obesity, insulin resistance, and diabetes.

Objectives

Our objective in this study was to investigate phthalate exposure and its associations with abdominal obesity and insulin resistance.

Citation impact

641

total citations

FWCI: 17.67
Percentile: 100%
References: 77

Citations per year

Authors

5

Topics & keywords

Topics

Keywords

Phthalate
National Health and Nutrition Examination Survey
Insulin resistance
Endocrinology
Waist
Internal medicine
Abdominal obesity
Medicine

UN Sustainable Development Goals

Zero hunger

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