Microcirculatory Alterations in Patients With Severe Sepsis

Sepsis induces microvascular alterations that may play an important role in the development of organ dysfunction. However, the relationship of these alterations to systemic variables and outcome is still not well defined. We investigated which factors may influence microcirculatory alterations in patients with severe sepsis and whether these are independently associated with mortality.

Analysis of prospectively collected data from previously published studies by our group.