MicroRNAs AND THEIR REGULATORY ROLES IN PLANTS
Howard Hughes Medical Institute · Whitehead Institute for Biomedical Research · +2 more institutions
Abstract
MicroRNAs (miRNAs) are small, endogenous RNAs that regulate gene expression in plants and animals. In plants, these approximately 21-nucleotide RNAs are processed from stem-loop regions of long primary transcripts by a Dicer-like enzyme and are loaded into silencing complexes, where they generally direct cleavage of complementary mRNAs. Although plant miRNAs have some conserved functions extending beyond development, the importance of miRNA-directed gene regulation during plant development is now particularly clear. Identified in plants less than four years ago, miRNAs are already known to play numerous crucial roles at each major stage of development-typically at the cores of gene regulatory networks,…
Citation impact
- FWCI
- 147.26
- Percentile
- 100%
- References
- 169
Authors
3- MWMatthew W. Jones-RhoadesCorresponding
Howard Hughes Medical Institute, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- DPDavid P. Bartel
Howard Hughes Medical Institute, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- BBBonnie Bartel
Rice University
Topics & keywords
- Dicer
- microRNA
- Biology
- Gene silencing
- Gene
- Argonaute
- Gene expression
- Regulation of gene expression