reviewBritish Journal of PharmacologyJan 5, 2015BRONZE OA

Transdermal patches: history, development and pharmacology

University of South Australia · University of Geneva · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Transdermal patches are now widely used as cosmetic, topical and transdermal delivery systems. These patches represent a key outcome from the growth in skin science, technology and expertise developed through trial and error, clinical observation and evidence-based studies that date back to the first existing human records. This review begins with the earliest topical therapies and traces topical delivery to the present-day transdermal patches, describing along the way the initial trials, devices and drug delivery systems that underpin current transdermal patches and their actives. This is followed by consideration of the evolution in the various patch designs and their limitations as well as requirements for…

Citation impact

562
total citations
FWCI
11.45
Percentile
100%
References
316
Citations per year

Authors

4

Topics & keywords

Keywords
  • Transdermal
  • Delivery system
  • Medicine
  • Drug delivery
  • Transdermal patch
  • Pharmacology
  • Skin barrier
  • Intensive care medicine
UN Sustainable Development Goals
  • Good health and well-being
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Funding