articleHypertensionApr 3, 2006BRONZE OA

Short Sleep Duration as a Risk Factor for Hypertension

JEJames E. GangwischSBSteven B. HeymsfieldBBBernadette Boden‐AlbalaRMRuud M. BuijsFKFelix Kreier

Merck & Co., Inc., Rahway, NJ, USA (United States) · Netherlands Institute for Neuroscience · +2 more institutions

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Abstract

Depriving healthy subjects of sleep has been shown to acutely increase blood pressure and sympathetic nervous system activity. Prolonged short sleep durations could lead to hypertension through extended exposure to raised 24-hour blood pressure and heart rate, elevated sympathetic nervous system activity, and increased salt retention. Such forces could lead to structural adaptations and the entrainment of the cardiovascular system to operate at an elevated pressure equilibrium. Sleep disorders are associated with cardiovascular disease, but we are not aware of any published prospective population studies that have shown a link between short sleep duration and the incidence of hypertension in subjects without…

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Topics
Keywords
  • Medicine
  • Blood pressure
  • Hazard ratio
  • Risk factor
  • Proportional hazards model
  • Confounding
  • Diabetes mellitus
  • Incidence (geometry)
UN Sustainable Development Goals
  • Good health and well-being
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