EGFR Antagonists in Cancer Treatment
University of Campania "Luigi Vanvitelli" · Institute for Experimental Endocrinology and Oncology · +1 more institution
Indexed incrossrefpubmed
Abstract
Functional activation of growth factors and receptors of the epidermal growth factor receptor (EGFR) family occurs in most epithelial-cell cancers, rendering EGFR a target for cancer treatment. This article discusses the mechanisms of action of EGFR inhibitors, their anticancer activity, and clinical issues concerning their use in the treatment of patients with cancer.
Citation impact
2,053
total citations
- FWCI
- 135.25
- Percentile
- 100%
- References
- 201
Citations per year
Authors
2Topics & keywords
Topics
Keywords
- Medicine
- Epidermal growth factor receptor
- EGFR inhibitors
- Receptor
- Cancer
- Cancer research
- Oncology
- Bioinformatics
UN Sustainable Development Goals
- Good health and well-being
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