The reporting odds ratio and its advantages over the proportional reporting ratio

The method used is discussion and illustration by way of a hypothetical example.

The PRR does not estimate relative risk. If, however, a spontaneous report database is viewed as source data for a case-control study, the reporting odds ratio (ROR) can be used to estimate relative risk. Treating the data as source data for a case-control study allows for further reduction of bias by the judicious choice of controls.