The Cancer Genome Atlas Pan-Cancer analysis project
The University of Texas MD Anderson Cancer Center · University of California, San Francisco · +6 more institutions
Abstract
Current clinical practice is organized according to tissue or organ of origin of tumors. Now, The Cancer Genome Atlas (TCGA) Research Network has started to identify genomic and other molecular commonalities among a dozen different types of cancer. Emerging similarities and contrasts will form the basis for targeted therapies of the future and for repurposing existing therapies by molecular rather than histological similarities of the diseases. The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture…
Citation impact
- FWCI
- 91.57
- Percentile
- 100%
- References
- 44
Authors
9- JNJohn N. WeinsteinCorresponding
The University of Texas MD Anderson Cancer Center
- EAEric A Collisson
University of California, San Francisco
- GBGordon B. Mills
The University of Texas MD Anderson Cancer Center
- KSKenna Shaw
The University of Texas MD Anderson Cancer Center, National Cancer Institute
- BOBrad Ozenberger
National Institutes of Health, National Human Genome Research Institute
Topics & keywords
- Biology
- Repurposing
- Computational biology
- Cancer
- Genome
- Genomics
- Epigenetics
- Bioinformatics