Sleep Duration and All-Cause Mortality: A Systematic Review and Meta-Analysis of Prospective Studies

A DAILY BASIS. ITS underlying mechanisms, interactions, and long-term effects are still poorly understood. Sleep patterns of quantity and quality are affected by a variety of cultural, social, psychological, behavioral, pathophysiological, and environmental influences and have shown secular trends alongside changes in the modern society requiring longer hours of work, more shift-work and 24-7 availability of commodities, curtailing the duration of sleep to fewer hours per day across westernized populations. 1 This has led to increased reporting of fatigue, tiredness, and excessive daytime sleepiness. 2 Lack of sleep also exerts deleterious effects on a variety of systems with detectable changes in metabolic,…

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