Efficiency and Fidelity in a Click‐Chemistry Route to Triazole Dendrimers by the Copper( I )‐Catalyzed Ligation of Azides and Alkynes
Scripps Research Institute · IBM Research - Almaden · +2 more institutions
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Abstract
Components that click: A large number of diverse dendrimers (see scheme) was prepared in almost quantitative yield by the click-chemistry transformation described in the title. In some cases filtration or solvent extraction was the only method required for purification in this highly efficient construction of the triazole units of the dendrimers.
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Topics
Keywords
- Click chemistry
- Dendrimer
- Chemistry
- Combinatorial chemistry
- Triazole
- Yield (engineering)
- Transformation (genetics)
- Copper
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