Breast Cancer Subtypes Based on ER/PR and Her2 Expression: Comparison of Clinicopathologic Features and Survival
Marshfield Clinic Weston Center · Marshfield Clinic · +1 more institution
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Abstract
Objective
To compare the clinicopathologic features and survival in the four breast cancer subtypes defined by immunohistochemistry (IHC) expression of estrogen receptor (ER) or progesterone receptor (PR) and human epidermal growth factor receptor 2 (Her2): ER/PR+, Her2+; ER/PR+, Her2-; ER/PR-, Her2+; and ER/PR-, Her2-.
Methods
A 7-year retrospective study of 1134 invasive breast cancer subjects. Clinical and pathologic features and survival of the four subtypes were compared.
Citation impact
847
total citations
- FWCI
- 12.09
- Percentile
- 100%
- References
- 36
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Authors
4Topics & keywords
Topics
Keywords
- Medicine
- Hazard ratio
- Estrogen receptor
- Breast cancer
- Oncology
- Immunohistochemistry
- Human Epidermal Growth Factor Receptor 2
- Internal medicine
UN Sustainable Development Goals
- Good health and well-being
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