articleNew England Journal of MedicineDec 27, 2006Closed access

An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU

PJPeter J. PronovostDMDale M. NeedhamSMSean M. BerenholtzDSDavid SinopoliHCHaitao Chu

Johns Hopkins Medicine · Johns Hopkins University · +6 more institutions

PubMed
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Abstract

Background

Catheter-related bloodstream infections occurring in the intensive care unit (ICU) are common, costly, and potentially lethal.

Methods

We conducted a collaborative cohort study predominantly in ICUs in Michigan. An evidence-based intervention was used to reduce the incidence of catheter-related bloodstream infections. Multilevel Poisson regression modeling was used to compare infection rates before, during, and up to 18 months after implementation of the study intervention. Rates of infection per 1000 catheter-days were measured at 3-month intervals, according to the guidelines of the National Nosocomial Infections Surveillance System.

Citation impact

4,360
total citations
FWCI
254.86
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100%
References
24
Citations per year

Authors

13

Topics & keywords

Topics
Keywords
  • Medicine
  • Catheter
  • Poisson regression
  • Confidence interval
  • Intensive care unit
  • Incidence (geometry)
  • Bloodstream infection
  • Rate ratio
UN Sustainable Development Goals
  • Good health and well-being
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