TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer
The University of Texas MD Anderson Cancer Center · Nanjing Medical University · +1 more institution
Abstract
Long noncoding RNAs (lncRNA) have emerged as essential players in cancer biology. Using recent large-scale RNA-seq datasets, especially those from The Cancer Genome Atlas (TCGA), we have developed "The Atlas of Noncoding RNAs in Cancer" (TANRIC; http://bioinformatics.mdanderson.org/main/TANRIC:Overview), a user-friendly, open-access web resource for interactive exploration of lncRNAs in cancer. It characterizes the expression profiles of lncRNAs in large patient cohorts of 20 cancer types, including TCGA and independent datasets (>8,000 samples overall). TANRIC enables researchers to rapidly and intuitively analyze lncRNAs of interest (annotated lncRNAs or any user-defined ones) in the context of clinical and…
Citation impact
- FWCI
- 21.23
- Percentile
- 100%
- References
- 36
Authors
8- JLJun LiCorresponding
The University of Texas MD Anderson Cancer Center
- LHLeng Han
The University of Texas MD Anderson Cancer Center
- PRPaul Roebuck
The University of Texas MD Anderson Cancer Center
- LDLixia Diao
The University of Texas MD Anderson Cancer Center
- LLLingxiang Liu
The University of Texas MD Anderson Cancer Center, Nanjing Medical University
Topics & keywords
- Computational biology
- Cancer
- Context (archaeology)
- Biology
- Function (biology)
- Bioinformatics
- Computer science
- Genetics