New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Dupuis, Josée; investigators, the MAGIC; Langenberg, Claudia; Prokopenko, Inga; Saxena, Richa; Soranzo, Nicole; Jackson, Anne; Wheeler, Eleanor; Glazer, Nicole L.; Bouatia‐Naji, Nabila; Gloyn, Anna L.; Lindgren, Cecilia M.; Mägi, Reedik; Morris, Andrew P.; Randall, Joshua C.; Johnson, Toby; Elliott, Paul; Rybin, Denis; Þorleifsson, Guðmar; Steinthórsdóttir, Valgerður; Henneman, Peter; Grallert, Harald; Dehghan, Abbas; Hottenga, Jouke‐Jan; Franklin, C.; Navarro, Pau; Song, Kijoung; Goel, Anuj; Perry, John R. B.; Egan, Josephine M.; Lajunen, Taina K.; Grarup, Niels; Sparsø, Thomas; Doney, Alex S. F.; Voight, Benjamin F.; Stringham, Heather M.; Li, Man; Kanoni, Stavroula; Shrader, Peter; Cavalcanti-Proença, Christine; Kumari, Meena; Qi, Lu; Timpson, Nicholas J.; Gieger, Christian; Aben, Katja K.H.; Rocheleau, Ghislain; Ingelsson, Erik; An, Ping; O’Connell, Jeffrey R.; Luan, Jian’an; Elliott, Amanda; McCarroll, Steven A.; Payne, Felicity; Roccasecca, Rosa Maria; Pattou, François; Sethupathy, Praveen; Ardlie, Kristin; Ariyürek, Yavuz; Balkau, Beverley; Barter, Philip J.; Beilby, John; Ben‐Shlomo, Yoav; Benediktsson, Rafn; Bennett, Amanda J.; Bergman, Richard N.; Bochud, Murielle; Boerwinkle, Eric; Bonnefond, Amélie; Bonnycastle, Lori L.; Borch‐Johnsen, Knut; Böttcher, Yvonne; Brunner, Eric J.; Bumpstead, Suzannah J.; Charpentier, G.; Chen, Yii‐Der Ida; Chines, Peter S.; Clarke, Robert; Coin, Lachlan; Cooper, Matthew N.; Cornelis, Marilyn C.; Crawford, Gabe; Crisponi, Laura; Day, Ian N.M.; Geus, Eco J. C. de; Delplanque, Jérôme; Dina, Christian; Erdos, Michael R.; Fedson, Annette C.; Fischer‐Rosinsky, Antje; Forouhi, Nita G.; Fox, Caroline S.; Frants, Rune R.; Franzosi, Maria Grazia; Galán, Pilar; Goodarzi, Mark O.; Graessler, J.; Groves, Christopher J.; Grundy, Scott M.; Gwilliam, Rhian; Gyllensten, Ulf; Hadjadj, Samy; Hallmans, Göran; Hammond, Naomi; Han, Xijing; Hartikainen, Anna‐Liisa; Hassanali, Neelam; Hayward, Caroline; Heath, Simon; Herçberg, Serge; Herder, Christian; Hicks, Andrew A.; Hillman, David R.; Hingorani, Aroon D.; Hofman, Albert; Hui, Jennie; Hung, Joe; Isomaa, Bo; Johnson, Paul R V; Jørgensen, Torben; Jula, Antti; Kaakinen, Marika; Kaprio, Jaakko; Kesäniemi, Y. Antero; Kivimäki, Mika; Knight, Beatrice; Koskinen, Seppo; Kovács, Péter; Kyvik, Kirsten Ohm; Lathrop, G.M.; Lawlor, Debbie A.; Bacquer, Olivier Le; Lecœur, Cécile; Li, Yun; Lyssenko, Valeriya; Mahley, Robert W.; Mangino, Massimo; Manning, Alisa K; Martin, Nicholas G.; McAteer, Jarred B.; McCulloch, Laura; McPherson, Ruth; Meisinger, Christa; Melzer, David; Eyre, Stephen; Mitchell, Braxton D.; Morken, Mario A.; Mukherjee, Sutapa; Naitza, Silvia; Narisu, Narisu; Neville, Matthew; Oostra, Ben A.; Orrù, Marco; Pakyz, Ruth; Palmer, Colin N A; Paolisso, Giuseppe; Pattaro, Cristian; Pearson, Daniel S.; Peden, John F.; Pedersen, Nancy L.; Perola, Markus; Pfeiffer, Andreas; Pichler, Irene; Polašek, Ozren; Posthuma, Daniëlle; Potter, Simon; Pouta, Anneli; Province, Michael A.; Psaty, Bruce M.; Rathmann, Wolfgang; Rayner, Nigel W.; Rice, Kenneth; Ripatti, Samuli; Rivadeneira, Fernando; Roden, Michael; Rolandsson, Olov; Sandbæk, Annelli; Sandhu, Manjinder S.; Sanna, Serena; Sayer, Avan Aihie; Scheet, Paul; Scott, Laura J.; Seedorf, Udo; Sharp, Stephen J.; Shields, Beverley M.; Sigurðsson, Gunnar; Sijbrands, Eric J.G.; Silveira, Angela; Simpson, Laila; Singleton, Andrew B.; Smith, Nicholas L.; Sovio, Ulla; Swift, Amy J.; Syddall, Holly; Syvänen, Ann‐Christine; Tanaka, Toshiko; Thorand, Barbara; Tichet, Jean; Tönjes, Anke; Tuomi, Tiinamaija; Uitterlinden, André G.; Dijk, Ko Willems van; Hoek, Mandy van; Varma, Dhiraj; Visvikis‐Siest, Sophie; Vitart, Véronique; Vogelzangs, Nicole; Waeber, Gérard; Wagner, Peter J.; Walley, Andrew J.; Walters, G. Bragi; Ward, Kim L; Watkins, Hugh; Weedon, Michael N.; Wild, Sarah H.; Willemsen, Gonneke; Witteman, J. C. M.; Yarnell, J. W. G.; Zeggini, Eleftheria; Zélénika, Diana; Zethelius, Björn; Zhai, Guangju; Zhao, Wei; Zillikens, M. Carola; Borecki, Ingrid B.; Loos, Ruth J. F.; Meneton, Pierre; Magnusson, Patrik K. E.; Nathan, David M.; Williams, Gordon H.; Hattersley, Andrew T.; Silander, Kaisa; Salomaa, Veikko; Smith, George Davey; Bornstein, Stefan R.; Schwarz, Peter E. H.; Spranger, Joachim; Karpe, Fredrik; Shuldiner, Alan R.; Cooper, Cyrus; Dedoussis, George; Serrano‐Ríos, Manuel; Morris, Andrew D.; Lind, Lars; Palmer, Lyle J.; Hu, Frank B.; Franks, Paul W.; Ebrahim, Shah; Marmot, Michael; Kao, W.H. Linda; Pankow, James S.; Sampson, Michael; Kuusisto, Johanna; Laakso, Markku; Hansen, Torben; Pedersen, Oluf; Pramstaller, Peter P.; Wichmann, H.‐Erich; Illig, Thomas; Rudan, Igor; Wright, Alan F.; Stümvoll, Michael; Campbell, Harry; Wilson, James F.

doi:10.1038/ng.520

articleNature GeneticsJan 17, 2010GREEN OA

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

JDJosée DupuisTMthe MAGIC investigatorsCLClaudia Langenberg IPInga Prokopenko RSRicha Saxena

Boston University · Addenbrooke's Hospital · +114 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

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2,225

total citations

FWCI: 128.18
Percentile: 100%
References: 78

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Authors

263

JD
Josée DupuisCorresponding
Boston University
TM
the MAGIC investigators
Addenbrooke's Hospital, MRC Epidemiology Unit, Medical Research Council
CL
Claudia Langenberg
University of Oxford, Oxford Centre for Diabetes, Endocrinology and Metabolism
IP
Inga Prokopenko
Broad Institute
RS
Richa Saxena
Wellcome Sanger Institute

Topics & keywords

Topics

Keywords

Biology
Insulin resistance
Type 2 diabetes
Glucose homeostasis
Internal medicine
Genome-wide association study
Glycemic
Endocrinology

UN Sustainable Development Goals

Good health and well-being

No related works found for this paper.

Funding

EA
Economic and Social Research Council
Award: ES/G007438/1