articleJNCI Journal of the National Cancer InstituteApr 28, 2014BRONZE OA

US Incidence of Breast Cancer Subtypes Defined by Joint Hormone Receptor and HER2 Status

Louisiana State University Health Sciences Center New Orleans · University of Washington · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Background

In 2010, Surveillance, Epidemiology, and End Results (SEER) registries began collecting human epidermal growth factor 2 (HER2) receptor status for breast cancer cases.

Methods

Breast cancer subtypes defined by joint hormone receptor (HR; estrogen receptor [ER] and progesterone receptor [PR]) and HER2 status were assessed across the 28% of the US population that is covered by SEER registries. Age-specific incidence rates by subtype were calculated for non-Hispanic (NH) white, NH black, NH Asian Pacific Islander (API), and Hispanic women. Joint HR/HER2 status distributions by age, race/ethnicity, county-level poverty, registry, stage, Bloom-Richardson grade, tumor size, and nodal status were evaluated using multivariable adjusted polytomous logistic regression. All statistical tests were two-sided.

No related works found for this paper.

Funding