Mapping the Structural Core of Human Cerebral Cortex

Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways. By using diffusion spectrum imaging, we noninvasively mapped these pathways within and across cortical hemispheres in individual human participants. An analysis of the resulting large-scale structural brain networks reveals a structural core within posterior medial and parietal cerebral cortex, as well as several distinct temporal and frontal modules. Brain regions within the structural core share high degree, strength, and betweenness centrality, and they constitute connector hubs that link all major structural modules. The structural core…

• JS
  James S. McDonnell Foundation
• ÉP
  École Polytechnique Fédérale de Lausanne
• UD
  Université de Lausanne
• CD
  Centre d'Imagerie BioMédicale
• CH
  Centre Hospitalier Universitaire Vaudois
• NI
  National Institutes of Health