Hemochromatosis and Iron-Overload Screening in a Racially Diverse Population
University of California, Irvine · London Health Sciences Centre · +10 more institutions
Abstract
Iron overload and hemochromatosis are common, treatable conditions. HFE genotypes, levels of serum ferritin, transferrin saturation values, and self-reported medical history were studied in a multiethnic primary care population.
Participants were recruited from primary care practices and blood-drawing laboratories. Blood samples were tested for transferrin saturation, serum ferritin, and C282Y and H63D mutations of the HFE gene. Before genetic screening, participants were asked whether they had a history of medical conditions related to iron overload.
Citation impact
- FWCI
- 26.43
- Percentile
- 100%
- References
- 33
Authors
16- PCPaul C. AdamsCorresponding
University of California, Irvine, London Health Sciences Centre
- DMDavid M. Reboussin
University of California, Irvine, Wake Forest University
- JCJames C. Barton
Southern Research Institute, University of California, Irvine
- CEChristine E. McLaren
University of California, Irvine
- JHJohn H. Eckfeldt
University of Minnesota
Topics & keywords
- Transferrin saturation
- Hemochromatosis
- Medicine
- Ferritin
- Serum iron
- Hereditary hemochromatosis
- Pacific islanders
- Internal medicine