SNPStats: a web tool for the analysis of association studies
Institut d'Investigació Biomédica de Bellvitge · Institut Català d'Oncologia · +1 more institution
Abstract
SUMMARY: A web-based application has been designed from a genetic epidemiology point of view to analyze association studies. Main capabilities include descriptive analysis, test for Hardy-Weinberg equilibrium and linkage disequilibrium. Analysis of association is based on linear or logistic regression according to the response variable (quantitative or binary disease status, respectively). Analysis of single SNPs: multiple inheritance models (co-dominant, dominant, recessive, over-dominant and log-additive), and analysis of interactions (gene-gene or gene-environment). Analysis of multiple SNPs: haplotype frequency estimation, analysis of association of haplotypes with the response, including analysis of…
Citation impact
- FWCI
- 17.15
- Percentile
- 100%
- References
- 4
Authors
5- XSXavier SoléCorresponding
Institut d'Investigació Biomédica de Bellvitge, Institut Català d'Oncologia
- EGElisabet Guinó
Institut d'Investigació Biomédica de Bellvitge, Institut Català d'Oncologia
- JVJoan Valls
Universitat Autònoma de Barcelona, Institut d'Investigació Biomédica de Bellvitge, Institut Català d'Oncologia
- RIRaquel Iniesta
Institut d'Investigació Biomédica de Bellvitge, Institut Català d'Oncologia
- VMVı́ctor Moreno
Universitat Autònoma de Barcelona, Institut d'Investigació Biomédica de Bellvitge, Institut Català d'Oncologia
Topics & keywords
- Linkage disequilibrium
- Genetic association
- Haplotype
- Single-nucleotide polymorphism
- Genetics
- Genetic analysis
- Logistic regression
- Computer science
- Good health and well-being