Automating network meta‐analysis
University Medical Center Groningen · University of Groningen
Abstract
Mixed treatment comparison (MTC) (also called network meta-analysis) is an extension of traditional meta-analysis to allow the simultaneous pooling of data from clinical trials comparing more than two treatment options. Typically, MTCs are performed using general-purpose Markov chain Monte Carlo software such as WinBUGS, requiring a model and data to be specified using a specific syntax. It would be preferable if, for the most common cases, both could be derived from a well-structured data file that can be easily checked for errors. Automation is particularly valuable for simulation studies in which the large number of MTCs that have to be estimated may preclude manual model specification and analysis.…
Citation impact
- FWCI
- 15.55
- Percentile
- 100%
- References
- 24
Authors
6- GVGert van ValkenhoefCorresponding
University Medical Center Groningen, University of Groningen
- GLGuobing Lu
University Medical Center Groningen, University of Groningen
- BDBert de Brock
University Medical Center Groningen, University of Groningen
- HLHans L. Hillege
University Medical Center Groningen, University of Groningen
- AEA. E. Ades
University Medical Center Groningen, University of Groningen
Topics & keywords
- Computer science
- Pooling
- Markov chain Monte Carlo
- Consistency (knowledge bases)
- Markov chain
- Software
- Data mining
- Bayesian probability