articleClinical Infectious DiseasesAug 25, 2003Closed access

A Prospective Observational Study of Candidemia: Epidemiology, Therapy, and Influences on Mortality in Hospitalized Adult and Pediatric Patients

PGPeter G. PappasJRJohn RexJLJ. LeeRJRichard J. HamillRARobert A. Larsen

University of Alabama at Birmingham · The University of Texas Health Science Center at Houston · +11 more institutions

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Abstract

We conducted a prospective, multicenter observational study of adults (n=1447) and children (n=144) with candidemia at tertiary care centers in the United States in parallel with a candidemia treatment trial that included nonneutropenic adults. Candida albicans was the most common bloodstream isolate recovered from adults and children (45% vs. 49%) and was associated with high mortality (47% among adults vs. 29% among children). Three-month survival was better among children than among adults (76% vs. 54%; P

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Topics & keywords

Topics
Keywords
  • Medicine
  • Fungemia
  • Fluconazole
  • Observational study
  • Candida glabrata
  • Candida parapsilosis
  • Internal medicine
  • Epidemiology
UN Sustainable Development Goals
  • Good health and well-being
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