Abnormal Rich Club Organization and Functional Brain Dynamics in Schizophrenia

The human brain forms a large-scale structural network of regions and interregional pathways. Recent studies have reported the existence of a selective set of highly central and interconnected hub regions that may play a crucial role in the brain's integrative processes, together forming a central backbone for global brain communication. Abnormal brain connectivity may have a key role in the pathophysiology of schizophrenia.

To examine the structure of the rich club in schizophrenia and its role in global functional brain dynamics.