Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina)
Los Alamos National Laboratory · Novozymes (Denmark) · +13 more institutions
Abstract
Trichoderma reesei is the main industrial source of cellulases and hemicellulases used to depolymerize biomass to simple sugars that are converted to chemical intermediates and biofuels, such as ethanol. We assembled 89 scaffolds (sets of ordered and oriented contigs) to generate 34 Mbp of nearly contiguous T. reesei genome sequence comprising 9,129 predicted gene models. Unexpectedly, considering the industrial utility and effectiveness of the carbohydrate-active enzymes of T. reesei, its genome encodes fewer cellulases and hemicellulases than any other sequenced fungus able to hydrolyze plant cell wall polysaccharides. Many T. reesei genes encoding carbohydrate-active enzymes are distributed nonrandomly in…
Citation impact
- FWCI
- 49.76
- Percentile
- 100%
- References
- 52
Authors
45- DMDiego MartinezCorresponding
Los Alamos National Laboratory
- RMRandy M. Berka
Novozymes (Denmark), Novozymes (United States)
- BHBernard Henrissat
Centre National de la Recherche Scientifique, Aix-Marseille Université, Architecture et Fonction des Macromolécules Biologiques
- MSMarkku Saloheimo
VTT Technical Research Centre of Finland
- MAMikko Arvas
VTT Technical Research Centre of Finland
Topics & keywords
- Trichoderma reesei
- Hypocrea
- Cellulase
- Genome
- Gene
- Biology
- Trichoderma
- Glycoside hydrolase