Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

Arnison, Paul G.; Bibb, Mervyn J.; Bierbaum, Gabriele; Bowers, Albert A.; Bugni, Tim S.; Bułaj, Grzegorz; Camarero, Julio A.; Campopiano, Dominic J.; Challis, Gregory L.; Clardy, Jon; Cotter, Paul D.; Craik, David J.; Dawson, Michael J.; Dittmann, Elke; Donadio, Stefano; Dorrestein, Pieter C.; Entian, Karl‐Dieter; Fischbach, Michael A.; Garavelli, John S.; Göransson, Ulf; Gruber, Christian W.; Haft, Daniel H.; Hemscheidt, Thomas; Hertweck, Christian; Hill, Colin; Horswill, Alexander R.; Jaspars, Marcel; Kelly, Wendy L.; Klinman, Judith P.; Kuipers, Oscar P.; Link, A. James; Liu, Wen; Marahiel, Mohamed A.; Mitchell, Douglas A.; Moll, Gert N.; Moore, Bradley S.; Müller, Rolf; Nair, Satish K.; Nes, Ingolf F.; Norris, Gillian E.; Olivera, Baldomero M.; Onaka, Hiroyasu; Patchett, Mark L.; Piel, Joern; Reaney, Martin J. T.; Rebuffat, Sylvie; Ross, R. Paul; Sahl, Hans‐Georg; Schmidt, Eric W.; Selsted, Michael E.; Severinov, Konstantin; Shen, Ben; Sivonen, Kaarina; Smith, Leif; Stein, Torsten; Süßmuth, Roderich D.; Tagg, John; Tang, Gong‐Li; Truman, Andrew W.; Vederas, John C.; Walsh, Christopher T.; Walton, Jonathan D.; Wenzel, Silke C.; Willey, Joanne M.; Donk, Wilfred A. van der

doi:10.1039/c2np20085f

reviewNatural Product ReportsNov 20, 2012Closed access

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

PGPaul G. Arnison MJMervyn J. Bibb GBGabriele Bierbaum AAAlbert A. Bowers TSTim S. Bugni

Genome Prairie · John Innes Centre · +26 more institutions

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Abstract

This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed.

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Topics & keywords

Topics

Keywords

Biosynthesis
Nomenclature
Computational biology
Peptide
Class (philosophy)
Combinatorial chemistry
Natural (archaeology)
Chemistry

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