LocusZoom: regional visualization of genome-wide association scan results
Calvin University · University of Michigan · +1 more institution
Abstract
UNLABELLED: Genome-wide association studies (GWAS) have revealed hundreds of loci associated with common human genetic diseases and traits. We have developed a web-based plotting tool that provides fast visual display of GWAS results in a publication-ready format. LocusZoom visually displays regional information such as the strength and extent of the association signal relative to genomic position, local linkage disequilibrium (LD) and recombination patterns and the positions of genes in the region. AVAILABILITY: LocusZoom can be accessed from a web interface at http://csg.sph.umich.edu/locuszoom. Users may generate a single plot using a web form, or many plots using batch mode. The software utilizes LD…
Citation impact
- FWCI
- 52.00
- Percentile
- 100%
- References
- 8
Authors
9- RPRandall PruimCorresponding
Calvin University, University of Michigan, National Human Genome Research Institute
- RWRyan Welch
Calvin University, University of Michigan, National Human Genome Research Institute
- SSSerena Sanna
Calvin University, University of Michigan, National Human Genome Research Institute
- TMTanya M. Teslovich
Calvin University, University of Michigan, National Human Genome Research Institute
- PSPeter S. Chines
Calvin University, University of Michigan, National Human Genome Research Institute
Topics & keywords
- dbSNP
- International HapMap Project
- Genome browser
- Genome-wide association study
- Computer science
- 1000 Genomes Project
- Linkage disequilibrium
- Genome