Nanoparticle Targeting of Anticancer Drug Improves Therapeutic Response in Animal Model of Human Epithelial Cancer

Kukowska‐Latallo, Jolanta F.; Candido, Kimberly A.; Cao, Zhengyi; Nigavekar, Shraddha S.; Majoros, István; Thomas, Thommey P.; Balogh, Lajos; Khan, Mohamed K.; Baker, James R.

doi:10.1158/0008-5472.can-04-3921

articleCancer ResearchJun 15, 2005BRONZE OA

Nanoparticle Targeting of Anticancer Drug Improves Therapeutic Response in Animal Model of Human Epithelial Cancer

JFJolanta F. Kukowska‐Latallo KAKimberly A. Candido ZCZhengyi Cao SSShraddha S. Nigavekar IMIstván Majoros

Michigan Medicine

PubMed

Indexed incrossrefpubmed

Abstract

Prior studies suggested that nanoparticle drug delivery might improve the therapeutic response to anticancer drugs and allow the simultaneous monitoring of drug uptake by tumors. We employed modified PAMAM dendritic polymers

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898

total citations

FWCI: 47.33
Percentile: 100%
References: 38

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Authors

9

Topics & keywords

Topics

Keywords

Folate receptor
Methotrexate
Pharmacology
Drug
Internalization
Targeted drug delivery
Chemistry
Drug delivery

UN Sustainable Development Goals

Good health and well-being

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