articleNature MethodsMar 2, 2014Closed access

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

BSBin ShenWZWensheng ZhangJZJun ZhangJZJiankui ZhouJWJian-Ying Wang

Model Animal Research Center · Nanjing University · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

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838
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FWCI
42.39
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100%
References
26
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Authors

11

Topics & keywords

Topics
Keywords
  • CRISPR
  • Genome editing
  • Cas9
  • Biology
  • Endonuclease
  • Genome
  • Computational biology
  • Genetics
UN Sustainable Development Goals
  • Zero hunger
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